China (Mainland)
Tofacitinib Citrate exporter suppliers 540737-29-9 in bulk supply CAS NO.540737-29-9
- Min.Order: 0 Metric Ton
- Payment Terms:
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Keywords
- Tofacitinib Citrate exporter
- suppliers 540737-29-9
- 540737-29-9 in bulk supply
Quick Details
- ProName: Tofacitinib Citrate exporter suppliers...
- CasNo: 540737-29-9
- Molecular Formula: C16H20N6O·C6H8O7
- Appearance: White crystal
- Application: Pharmaceutical excipient
- DeliveryTime: Prompt
- PackAge: 1kg/bag, 5kg/drum, 25kg/drum
- Port: According to details
- ProductionCapacity: Metric Ton/Day
- Purity: ≥99%
- Storage: Stored in a cool and dry well-closed c...
- Transportation: By air/by sea/by courier
- LimitNum: 0 Metric Ton
- Residue on Ignition: Not more than 0.1%
- Heavy Metal: Not more than 10 ppm
- Voluntary Standards: CP/In-house standard
Superiority
Tofacitinib Citrate exporter suppliers 540737-29-9 in bulk supply
Tofacitinib citrate, chemically called 3-(3R, 4R)-4-methyl-3-(7H-tuck and 2,3-d) On November 6, 2012, the U.S. Food and Drug Administration (FDA) and Pfizer jointly announced that Tofatinib is approved for use in adult patients with moderate to severe active rheumatoid arthritis (RA) who are inadequate or intolerant of metformin treatment, and Tofacitinib is the pioneering drug developed for rheumatoid arthritis treatment, known as Xeljanz.
Tofatinib can effectively choose to inhibit JAK3, and at the same time, JAK1, JAK2 also has inhibitory effect, thus blocking a series of jaKs-mediated cytokine signaling pathways in the system of abnormal cytokine level, inhibiting the transmission of abnormal immune signals, effectively controlling the RA course, the inhibition effect of other tyrosine kinase is weak, can reduce the range of adverse reactions
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