Entecavir Best price Buy 209216-23-9 High quality CAS NO.209216-23-9

Entecavir Best price Buy 209216-23-9 High quality

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1. Mixed container, we can mix different items in one container.

2. Quality control, with ISO certificate

3. Prompt shipment with professional documents.

4. Packing as your request, with photos before shipment.

5. High quality and competitive price

Hunan Warrant Chemical Co., Ltd. is a pharmaceutical research and development and production management
In May 2003, the company was recognized as a high-tech enterprise by the science and technology department of hunan province, and it is also one of the first backbone enterprises in liuyang bio-medicine industrial base of national torch plan.

 

Product Description

Entecavir is an antiviral nucleoside analog of 2'-deoxyguanosine (Item No. 9002864) and inhibitor of hepatitis B virus (HBV) reverse transcriptase (IC₅₀ = 0.5 nM). It undergoes phosphorylation by cellular kinases to its active form, entecavir triphosphate. Entecavir reduces virion DNA in the culture supernatant of HepG2 2.2.15 cells infected with hepatitis B virus (HBV; EC₅₀ = 3.75 nM). It reduces serum and hepatic levels of viral DNA in a duckling model of HBV infection when administered at a dose of 1 mg/kg. Formulations containing entecavir have been used in the treatment of chronic HBV infection.

Technical Information

Formal Name

2-amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one, monohydrate

CAS Number

209216-23-9

Synonyms

• BMS 200475
• SQ 34,676

Molecular Formula

C₁₂H₁₅N₅O₃ • H₂O

Formula Weight

295.3

Purity

≥95%

Formulation

A crystalline solid

Solubility

• DMF: 14 mg/ml
• DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml
• DMSO: 12 mg/ml
• Ethanol: 0.1 mg/ml

λ_max

256 nm

SMILES

NC(NC1=C2N=CN1[C@H]3C[C@H](O)[C@@H](CO)C3=C)=NC2=O.O

InChi Code

InChI=1S/C12H15N5O3.H2O/c1-5-6(3-18)8(19)2-7(5)17-4-14-9-10(17)15-12(13)16-11(9)20;/h4,6-8,18-19H,1-3H2,(H3,13,15,16,20);1H2/t6-,7-,8-;/m0./s1

InChi Key

YXPVEXCTPGULBZ-WQYNNSOESA-N

Shipping & Storage Information

Storage

-20°C

Shipping

Room Temperature in continental US; may vary elsewhere

Stability

≥ 2 years