Entecavir Fast delivery 209216-23-9 good producer on hot selling CAS NO.209216-23-9

Entecavir Fast delivery 209216-23-9 good producer on hot selling 

In human HepG2 cells transfected with wild hepatitis B virus, Entikawe inhibited 50% of the concentration required for viral DNA synthesis (EC50) of 0.004 m. The median EC50 value of Ntikawe's drug-resistant strain of Lamivdin (rtL180M, rtM204V) is 0.026 m (range 0.01 to 0.059 m), while Ntikave has no clinically related activity (EC50> for type 1 human immunodeficiency virus (HIV) grown in cell culture fluid 10μm)。 Daily or weekly use of this product can reduce the LEVEL of hepatitis virus DNA in North American guinea pigs and ducks. Long-term studies of five North American terraquins have shown that oral 0.5mg/kg ntekave per week (equivalent to a dose of 1.0mg in humans) keeps the viral DNA of three of them at unfathomable levels (viral DNA levels <200 copies/mL, PCR) for up to three years. In any animal treated with the drug for up to 3 years, no changes in HBV polyenzyme associated with enticave resistance were found.

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