Fosfomycin Trometamol in bulk supply 78964-85-9 in china in stock78964-85-9 CAS NO.78964-85-9

Fosfomycin Trometamol in bulk supply 78964-85-9 in china in stock 78964-85-9

Fosfomycin Tromethamine is the tromethamine salt form of fosfomycin, a synthetic broad-spectrum antibiotic. Fosfomycin tromethamine binds to and inactivates the enzyme enolpyruvyl transferase. This leads to an irreversible blockage of the condensation of uridine diphosphate-N-acetylglucosamine with p-enolpyruvate, which is one of the first steps of bacterial cell wall synthesis, thereby eventually causing cell lysis. In addition, fosfomycin tromethamine reduces the adherence of bacteria to uroepithelial cells. (NCI05)
1. High quality with competitive price:Our advantages :

We are manufacturer and we have 2 factories in China,we can provide excellent quality products with factory price.

2. Fast and safe delivery:
1) Parcels can be sent out within 3 days after payment. Tracking number is available.
2) Secure and discreet shipment. You have various choices of transportation methods.

3. We have clients throughout the world:
1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet your desire.
2) Market feedback and goods feedback are appreciated, meeting customers's requirement is our  responsibility.
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.

4. Exported areas:

Europe , southeast Asia , the Middle East , Africa , South America and some other countries and areas.
 
5. We manufacture Herbal Extract and Active Pharmaceutical Ingredients products.

Business scope: the pharmaceutical industry with professional import&export services of APIs and Intermediates as well as Herbal Extracts.

Product Description:

Fosfomycin trometamol is a broad-spectrum antibiotic that is active against Gram-negative and Gram-positive bacteria with MIC₉₀ values of 8, 32, 4, and 32 µg/mL for ESBL E. coli, carbapenemase-producing K. pneumoniae, P. mirabilis, and methicillin-resistant S. saprophyticus, respectively, in a broth microdilution assay. It is an inhibitor of uridine diphospho-N-acetyl-D-glucosamine enolpyruvyl transferase (MurA) that enters cells via the glycerol-3-phosphate and hexose-6-phosphate transporters.Formulations containing fosfomycin trometamol have been used in the treatment of urinary tract infections.

Formal Name

P-[(2R,3S)-3-methyl-2-oxiranyl]-phosphonic acid compound with 2-amino-2-(hydroxymethyl)-1,3-propanediol

CAS Number

78964-85-9

Synonyms

• Fosfomycin Tromethamine

Molecular Formula

C₄H₁₁NO₃ • C₃H₇O₄P

Formula Weight

259.2

Purity

≥98%

Formulation

A solid

Solubility

• Ethanol: Slightly Soluble
• Water: Soluble

SMILES

C[C@H]1[C@@H](P(O)(O)=O)O1.OCC(CO)(N)CO

InChi Code

InChI=1S/C4H11NO3.C3H7O4P/c5-4(1-6,2-7)3-8;1-2-3(7-2)8(4,5)6/h6-8H,1-3,5H2;2-3H,1H3,(H2,4,5,6)/t;2-,3+/m.0/s1

InChi Key

QZJIMDIBFFHQDW-LMLSDSMGSA-N

About us:

Hunan Warrant Chemical Co., Ltd was founded in Feburary 2017, is a subsidiary of Hunan Warrant Pharmaceutical Co., Ltd, providing the pharmaceutical industry with professional import&export services of APIs and Intermediates as well as Herbal Extracts.

Hunan Warrant Chemical Co., Ltd. is a pharmaceutical research and development and production management
In May 2003, the company was recognized as a high-tech enterprise by the science and technology department of hunan province, and it is also one of the first backbone enterprises in liuyang bio-medicine industrial base of national torch plan.

Since the establishment of the company in 2001, the company has made use of its own capital, talent, information and new drug research and development advantages, on the one hand, focusing on the research and development of new drugs, in a relatively short period of time to complete a series of new drug research and development work. With zhejiang sea is pharmaceutical co., LTD., China medicine group pharmaceutical co., LTD, hainan and brent pharmaceutical co., LTD., keep love some domestic well-known enterprises such as blessed pharmaceutical co., LTD. Signed a number of technology transfer agreement, from 2001 to now realized total technology transfer contract amount is 16.1 million yuan, become a rising star in the field of new drug technology development in hunan province. A solid preparation workshop with an annual production capacity of 200 million tablets, 200 million capsules and 50 million packets of granules and an active drug production workshop with an annual production capacity of 500 tons (mainly producing active drug disodium hydrogen phosphate and sodium dihydrogen phosphate) has been built. In December 2003, all the production workshops of the company have passed the national GMP on-site inspection and obtained the GMP certificate

On the other hand, the company strengthens the construction of production facilities. With the approval of Hunan Provincial Drug Administration, the company has set up a modern production workshop in Liuyang Biological Medicine Park that meets the requirements of GMP. The first-phase project investment is more than 20 million yuan.

The parent company is Hunan Warrant Pharmaceutical Co., Ltd, a High-tech joint-stock company founded in 2001, devoted to pharmaceutical industry with 3 GMP certified production bases and 2 R&D center, equipped with state of art instruments and machines, all located in environmental friendly industry park to support our sustainable development.