Entecavir exporter white solid 209216-23-9 factory supply CAS NO.209216-23-9

Entecavir exporter white solid 209216-23-9 factory supply

Entikave is a new type of cyclotyl bird glycoside anti-hepatitis B virus drug, the pharmacological effect is similar to Enticave, clinically applicable to the treatment of viral replication activity, serum transaminase ALT continued to rise or liver histology shows active lesions of chronic adult hepatitis B. This product is a nucleoside analogue of ostrich, which inhibits hepatitis B virus (HBV) polyenzyme. It can be phosphate-based to become an active triphosphate, which has a half-life of 15 hours in the cell. By competing with the natural substrate of HBV polyenzyme, triphosphate deoxygenated ostrich nucleosides, Ntekave triphosphate inhibits all three activities of viral polyenzyme (reverse transcriptase):

(1) the initiation of HBV polyenzyme.

(2) The formation of the pre-genome mRNA reverse transcription negative chain.

(3) Synthesis of HBVDNA positive chains. The inhibition constant (Ki) of Ntikawe triphosphate to HBVDNA polyenzyme was 0.0012 m. Entikave triphosphate inhibits cell α, β, niobium DNA polyenzyme, and mitochondrial gamma DNA polyenzyme, with a Ki value of 18 to 160 m.

1. Are you a trading company or a factory?   
We are a factory with our own trading company.  
2. How do you control quality?   
Our factory is equipped with professional and technical personnel for quality control, external inspectors every 2 hours to take samples for testing to ensure the quality of our production. We also accept BV, SGS or any other third party inspection.   
3. How do I start an order or payment? 
After confirming the order, a pro forma invoice will be sent with our bank information. Pay via T/T, .   
4. How to confirm the quality of the product before placing an order? 
  You can get free samples of some products, you only need to pay shipping costs or arrange for courier to send us samples. 
  You can send us your product specifications and requirements and we will manufacture the product according to your requirements.
5 . Can I get some samples? 
Yes, we can provide free samples, but shipping is paid for by our customers. 
6 . What is the delivery time?  
Small orders we ship within 3 days, and bulk orders we ship within 7-10 days.